Search results for "methods [Protein Interaction Mapping]"
showing 10 items of 252 documents
Theory of the growth mode for a thin metallic film on an insulating substrate
2002
We have developed a novel theory predicting the growth mode of a thin metallic film on an insulating substrate. This combines ab initio electronic structure calculations for several ordered metal/insulator interfaces (varying both coverage and substrate lattice constant), with a thermodynamic approach based on microscopic calculations. We illustrate this approach for Ag film deposited on MgO(0 0 1) substrate. Ab initio calculations predict high mobility of adsorbed silver atoms on the perfect magnesia surface even at low temperatures. Our theoretical analysis clearly demonstrates that the growth of metallic islands is predominant at the initial stage of silver deposition, which agrees with …
Dans quelle mesure les préférences individuelles contraignent-elles le développement du marché de l'assurance dépendance ?
2015
Dans un contexte de vieillissement de la population, différents scenarii sont envisagés pour réformer l’organisation et le financement de la prise en charge des personnes âgées dépendantes. La place de la prévoyance individuelle dans le financement de la dépendance est à ce titre largement débattue. À l’heure actuelle, malgré des restes à charge potentiellement conséquents, peu d’individus disposent d’une couverture assurantielle. Cet article vise à enrichir la littérature existante en évaluant dans quelle mesure les préférences observées dans la population limitent cette couverture. Nous mobilisons pour cela l’enquête Patrimoine et préférences vis-à-vis du temps et du risque (Pater) de 201…
ChIP-Seq from Limited Starting Material of K562 Cells and Drosophila Neuroblasts Using Tagmentation Assisted Fragmentation Approach
2019
Chromatin immunoprecipitation is extensively used to investigate the epigenetic profile and transcription factor binding sites in the genome. However, when the starting material is limited, the conventional ChIP-Seq approach cannot be implemented. This protocol describes a method that can be used to generate the chromatin profiles from as low as 100 human or 1,000 Drosophila cells. The method employs tagmentation to fragment the chromatin with concomitant addition of sequencing adaptors. The method generates datasets with high signal to noise ratio and can be subjected to standard tools for ChIP-Seq analysis.
Lifetime of the superconductive state in short and long Josephson junctions
2008
We study the transient statistical properties of short and long Josephson junctions under the influence of thermal and correlated fluctuations. In particular, we investigate the lifetime of the superconductive metastable state finding the presence of noise induced phenomena. For short Josephson junctions we investigate the lifetime as a function both of the frequency of the current driving signal and the noise intensity and we find how these noise-induced effects are modified by the presence of a correlated noise source. For long Josephson junctions we integrate numerically the sine-Gordon equation calculating the lifetime as a function of the length of the junction both for inhomogeneous a…
Efficient Analysis of Arbitrarily Shaped Inductive Obstacles in Rectangular Waveguides Using a Surface Integral Equation Formulation
2007
In this paper we propose to use the Surface Integral Equation technique for the analysis of arbitrarily shaped Hplane obstacles in rectangular waveguides, which can contain both metallic and/or dielectric objects. The Green functions are formulated using both spectral and spatial images series, whose convergence behavior has been improved through several acceleration techniques. Proceeding in this way, the convergence of the series is not attached to the employment of any particular basis or test function, thus consequently increasing the flexibility of the implemented technique. In order to test the accuracy and numerical efficiency of the proposed method, results for practical microwave c…
Engaging universities in social innovation research for understanding sustainability issues
2017
International audience; The paper presents the analysis of a three-stage research conducted by the authors within a social innovation project in collaboration with international master students of Riga Technical University for determining the factors, which motivate people to be involved in the solution of social problems. The authors not only analyse and use the outcomes of the students’ research but also provide feasibility study of using the potential of study research at the university, for implementing serious research projects. Data collection from Africa, Asia, America and Europe was organised jointly by all the students via web-based survey for creating an original data base for the…
Fast simulation of muons produced at the SHiP experiment using Generative Adversarial Networks
2019
This paper presents a fast approach to simulating muons produced in interactions of the SPS proton beams with the target of the SHiP experiment. The SHiP experiment will be able to search for new long-lived particles produced in a 400~GeV$/c$ SPS proton beam dump and which travel distances between fifty metres and tens of kilometers. The SHiP detector needs to operate under ultra-low background conditions and requires large simulated samples of muon induced background processes. Through the use of Generative Adversarial Networks it is possible to emulate the simulation of the interaction of 400~GeV$/c$ proton beams with the SHiP target, an otherwise computationally intensive process. For th…
Cellular world simulation: A collaborative model for spatial visioning and Territorial Intelligence.
2006
International audience; Urban sprawl is a typical problem that cannot be correctly understood and resolved because it relies on several different fields and concerns different actors. With traditional approaches, the whole process cannot be apprehended. This context partly explains the inefficiency of traditional planners' works, and asks for urban planning considered through the idea of collaborative projects. The CamDeus (Cellular Automata Models to Design Environmental and Urban Systems) project is an operational decision-making software giving cartographic and mathematical solutions in order to harmonize and share data and knowledge among scientists, territorial or administrative techni…